5-Chloro-1,3-dihydro-2H-pyrrolo[2,3-b]pyridin-2-one

5-Chloro-1,3-dihydro-2H-pyrrolo[2,3-b]pyridin-2-one - Names and Identifiers

Name	5-Chloro-1,3-dihydro-2H-pyrrolo[2,3-b]pyridin-2-one
Synonyms	5-chloro-7-aza-2-oxindole 5-Chloro-1H-pyrrolo[2,3-b... 5-Chloro-1H-pyrrolo[2,3-b]pyridin-2(3H) 5-Chloro-1H-pyrrolo[2,3-b]pyridin-2(3H)-one 5-chloro-1H,2H,3H-pyrrolo[2,3-b]pyridin-2-one 5-Chloro-1,3-dihydropyrrolo[2,3-b]pyridin-2-one 5-Chloro-1,3-dihydro-2H-pyrrolo[2,3-b]pyridin-2-one 2H-Pyrrolo[2,3-b]pyridin-2-one, 5-chloro-1,3-dihydro-
CAS	1190314-60-3
EINECS	200-258-5
InChI	InChI=1S/C7H5ClN2O/c8-5-1-4-2-6(11)10-7(4)9-3-5/h1,3H,2H2,(H,9,10,11)

5-Chloro-1,3-dihydro-2H-pyrrolo[2,3-b]pyridin-2-one - Physico-chemical Properties

Molecular Formula	C7H5ClN2O
Molar Mass	168.58
Density	1.450
Storage Condition	Sealed in dry,Room Temperature
Sensitive	Irritant
MDL	MFCD12962791

5-Chloro-1,3-dihydro-2H-pyrrolo[2,3-b]pyridin-2-one - Introduction

5-Chloro-7-aza-indol-2-one is an organic compound with the chemical formula C9H5ClN2O. The following is a description of its nature, use, preparation and safety information:

Nature:
1. Appearance: 5-chloro -7-aza-indole -2-one is a white crystalline solid.
2. melting point: its melting point is about 124-126°C.
3. Solubility: Soluble in some organic solvents (such as ether, chloroform), but insoluble in water.
4. Chemical properties: It is a heterocyclic compound containing chlorine and nitrogen heteroatoms, which can be used as a reagent for various chemical reactions.

Use:
1. 5-Chloro-7-aza-indol-2-one is commonly used as a reagent in organic synthesis and is used in the synthesis of other compounds.
2. It can also be used as a drug intermediate to participate in the synthesis of some drugs.

Preparation Method:
The preparation of 5-chloro-7-aza-indol-2-one can be carried out by nitrogen hybridization and chlorination using indole as a raw material. Specific synthetic methods may employ the phenolic amine substitution methods described in the literature.

Safety Information:
1. 5-Chloro-7-aza-indol-2-one is generally stable under normal conditions of use. However, during storage and handling, care should be taken to prevent contact with ignition sources and strong oxidants.
2. it is an organic synthesis reagent, work should follow the chemical laboratory safety procedures, the correct wear personal protective equipment, such as laboratory gloves, protective glasses and laboratory coats.
3. In the process of using 5-chloro-7-aza-indol-2-one, pay attention to avoid direct contact with skin, eyes and respiratory tract. In case of accidental contact, rinse immediately with plenty of water and seek medical help.

Please note that the safe handling of organic compounds is very important, and the relevant safety data sheets and chemical experimental procedures should be read and followed carefully before any handling.

Last Update：2024-04-09 20:45:29